SOFTWARE-AIDED APPROACH TO INVESTIGATE PEPTIDE STRUCTURE AND METABOLIC SUSCEPTIBILITY OF AMIDE BONDS IN PEPTIDE DRUGS BASED ON HIGH RESOLUTION MASS SPECTROMETRY.

Software-aided approach to investigate peptide structure and metabolic susceptibility of amide bonds in peptide drugs based on high resolution mass spectrometry.

Interest in using peptide molecules as therapeutic agents due to high selectivity and efficacy is increasing within the pharmaceutical industry.However, most peptide-derived drugs cannot be administered orally because of low bioavailability S2 ORANGE and instability in the gastrointestinal tract due to protease activity.Therefore, structural modifi

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